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Transcription profiling of CEPH individuals from the International HapMap Project

ABSTRACT: Baseline expression levels of genes in CEPH individuals from the International HapMap Project were measured using the Affymetrix Human Genome Focus Arrays. Arrays were analyzed using MAS 5.0 software (Affymetrix).

ORGANISM(S): Homo sapiens

SUBMITTER: Michael Morley

PROVIDER: E-GEOD-2552 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Mapping determinants of human gene expression by regional and genome-wide association.

Cheung Vivian G VG Spielman Richard S RS Ewens Kathryn G KG Weber Teresa M TM Morley Michael M Burdick Joshua T JT

Nature 20051001 7063

To study the genetic basis of natural variation in gene expression, we previously carried out genome-wide linkage analysis and mapped the determinants of approximately 1,000 expression phenotypes. In the present study, we carried out association analysis with dense sets of single-nucleotide polymorphism (SNP) markers from the International HapMap Project. For 374 phenotypes, the association study was performed with markers only from regions with strong linkage evidence; these regions all mapped ...[more]

PMID: 16251966

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