Ontology highlight
ABSTRACT:
ORGANISM(S): Drosophila melanogaster
SUBMITTER: Jason Grundstad
PROVIDER: E-GEOD-25569 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Nègre Nicolas N Brown Christopher D CD Ma Lijia L Bristow Christopher Aaron CA Miller Steven W SW Wagner Ulrich U Kheradpour Pouya P Eaton Matthew L ML Loriaux Paul P Sealfon Rachel R Li Zirong Z Ishii Haruhiko H Spokony Rebecca F RF Chen Jia J Hwang Lindsay L Cheng Chao C Auburn Richard P RP Davis Melissa B MB Domanus Marc M Shah Parantu K PK Morrison Carolyn A CA Zieba Jennifer J Suchy Sarah S Senderowicz Lionel L Victorsen Alec A Bild Nicholas A NA Grundstad A Jason AJ Hanley David D MacAlpine David M DM Mannervik Mattias M Venken Koen K Bellen Hugo H White Robert R Gerstein Mark M Russell Steven S Grossman Robert L RL Ren Bing B Posakony James W JW Kellis Manolis M White Kevin P KP
Nature 20110301 7339
Systematic annotation of gene regulatory elements is a major challenge in genome science. Direct mapping of chromatin modification marks and transcriptional factor binding sites genome-wide has successfully identified specific subtypes of regulatory elements. In Drosophila several pioneering studies have provided genome-wide identification of Polycomb response elements, chromatin states, transcription factor binding sites, RNA polymerase II regulation and insulator elements; however, comprehensi ...[more]