Gene expression data for two xenograft models representing luminal-like and basal-like breast cancer
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Eldrid Borgan
PROVIDER: E-GEOD-25915 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Distinct choline metabolic profiles are associated with differences in gene expression for basal-like and luminal-like breast cancer xenograft models.
Moestue Siver A SA Borgan Eldrid E Huuse Else M EM Lindholm Evita M EM Sitter Beathe B Børresen-Dale Anne-Lise AL Engebraaten Olav O Maelandsmo Gunhild M GM Gribbestad Ingrid S IS
BMC cancer 20100817
<h4>Background</h4>Increased concentrations of choline-containing compounds are frequently observed in breast carcinomas, and may serve as biomarkers for both diagnostic and treatment monitoring purposes. However, underlying mechanisms for the abnormal choline metabolism are poorly understood.<h4>Methods</h4>The concentrations of choline-derived metabolites were determined in xenografted primary human breast carcinomas, representing basal-like and luminal-like subtypes. Quantification of metabol ...[more]
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