Ontology highlight
ABSTRACT:
ORGANISM(S): Leucoraja erinacea
SUBMITTER: Benjamin King
PROVIDER: E-GEOD-26235 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
King Benjamin L BL Gillis J Andrew JA Carlisle Heather R HR Dahn Randall D RD
Science (New York, N.Y.) 20111201 6062
Hox proteins are a metazoan-specific family of transcription factors that are required for developmental patterning. The genomic arrangement of Hox genes into four paralogous clusters is a primitive feature of jawed vertebrates. By using high-throughput sequencing, we demonstrate the absence of all HoxC transcripts from embryos of the shark Scyliorhinus canicula and the skate Leucoraja erinacea and the absence of all HoxC genes and two HoxC-associated microRNAs from the genome of L. erinacea. Th ...[more]