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Targeting of mitochondrial Hsp90 with Gamitrinib, G-TPP, in U251 glioblastoma cells

ABSTRACT: U251 gliolbastoma cells were treated with vehicle (DMSO) or G-TPP, a mitochondrial targeted version of 17-AAG. 6 hours after treatment RNA was harvested and subjected to microarray analysis on Human Gene 1.0 ST Array. We sought to determine a mitochdondrial gene response after targeting inhibition of mitochondrial chaperones, Hsp90.

ORGANISM(S): Homo sapiens

SUBMITTER: Markus Siegelin

PROVIDER: E-GEOD-26313 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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