Respiratory chain protein analysis and gene expression profiles of fibroblast cell lines from 9 patients with SURF1 gene mutations
Ontology highlight
ABSTRACT: Upregulation of CI, CIII and CV at a protein but not mRNA level in LSCOX cell with COX deficiency due to SURF1 mutations compared to control – evidence for posttranscriptional compensatory mechanism. Two-condition experiment, patients vs. controls cells. Biological replicates: 3 controls and 9 patients, independently grown and harvested.
ORGANISM(S): Homo sapiens
SUBMITTER: Viktor Stranecky
PROVIDER: E-GEOD-26322 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
ACCESS DATA