Hepatic induction of cholesterol biosynthesis reflects a remote adaptive response to pneumococcal pneumonia
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ABSTRACT: Transcriptional effects in liver, lung and blood samples from mice after intratracheal challenge with either Streptococcus pneumoniae serotype 19 (lobar-pneumonia) or serotype 2 (sepsis) were monitored after 6 and 24 hours and compared to sham (vehicle control). We gratefully acknowledge the BMBF grant within the “Promoting global research excellence in severe sepsis” (PROGRESS) study (01KI07111). Three tissues x two serotypes x two time resolved treatment groups x four replicates, three tissues x Sham Control x three replicates.
ORGANISM(S): Mus musculus
SUBMITTER: S. Lambeck
PROVIDER: E-GEOD-26472 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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