Gene expression data from treated LNCaP prostate cells.
Ontology highlight
ABSTRACT: Prostate cancer is dependent on androgen receptor (AR) signaling at all stages of the disease and cyclin D1 has been shown to negatively modulate the expression of the AR-dependent gene prostate specific antigen (KLK3/PSA). Unbiased gene expression profiling was performed to determine the androgen-regulated geneset that is sensitive to cyclin D1. Androgen-sensitive LNCaP cells were straved of androgen, then transduced with control green fluorescent protein (GFP) or cyclin D1 (CCND1) adenovirus, then subsequently stimulated with control (Ethanol) or dihydrotestosterone (DHT).
ORGANISM(S):  Homo sapiens 
SUBMITTER: Clay Comstock  
PROVIDER: E-GEOD-26483 | biostudies-arrayexpress |  
REPOSITORIES:  biostudies-arrayexpress
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