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Changes in the expression of miRs in the aorta after 3 and 10 months of a high fat diet compared with normal diet

ABSTRACT: We tried to identify miRs that are differentially expresssed during atherogenesis. Aortic miRs expression profile in female apoe-/- mice after 3 and 10 months of a high fat diet were compared with female apoe-/- mice on normal diet. 4 Female apoe-/- mice (6-8 weeks) were fed on high fat diet for 3 months. 3 female apoe-/- mice (6-8 weeks) were fed on high fat diet for 10 months. 4 female apoe-/- mice (6-8 weeks) on normal diet served as controls. Total RNA was isolated from whole aortic tissue. RNA samples with RIN>8 were used for array. The aortic miRs expression profile after 3 months of a high fat diet was compared with the control group. Biological replicates: 4 per group. One replicate per array.

ORGANISM(S): Mus musculus

SUBMITTER: Andreas Schober

PROVIDER: E-GEOD-26557 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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