Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Johannes Rainer
PROVIDER: E-GEOD-2677 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Schmidt Stefan S Rainer Johannes J Riml Stefan S Ploner Christian C Jesacher Simone S Achmüller Clemens C Presul Elisabeth E Skvortsov Sergej S Crazzolara Roman R Fiegl Michael M Raivio Taneli T Jänne Olli A OA Geley Stephan S Meister Bernhard B Kofler Reinhard R
Blood 20051117 5
The ability of glucocorticoids (GCs) to kill lymphoid cells led to their inclusion in essentially all chemotherapy protocols for lymphoid malignancies, particularly childhood acute lymphoblastic leukemia (ALL). GCs mediate apoptosis via their cognate receptor and subsequent alterations in gene expression. Previous investigations, including expression profiling studies with subgenome microarrays in model systems, have led to a number of attractive, but conflicting, hypotheses that have never been ...[more]