Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Kevil Christopher
PROVIDER: E-GEOD-27302 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Fang Kai K Zhang Songlin S Glawe John J Grisham Matthew B MB Kevil Christopher G CG
Inflammatory bowel diseases 20111216 8
<h4>Background</h4>T cells critically regulate inflammatory bowel disease (IBD), with T-cell-dependent experimental colitis models gaining favor in identifying potential pathogenic mechanisms; yet limited understanding of specific pathogenic molecules or pathways still exists.<h4>Methods</h4>In this study we sought to identify changes in whole genome expression profiles using the CD4CD45Rbhi T-cell transfer colitis model compared to genome expression differences from Crohn's disease (CD) tissue ...[more]