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Transcription profiling of human muscle tissue in patients with inflammatory myopathies

ABSTRACT: Molecular profiles of muscle tissue in patients with inflammatory myopathies

ORGANISM(S): Homo sapiens

SUBMITTER: Steven Alan Greenberg

PROVIDER: E-GEOD-281 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Molecular profiles of inflammatory myopathies.

Greenberg S A SA Sanoudou D D Haslett J N JN Kohane I S IS Kunkel L M LM Beggs A H AH Amato A A AA

Neurology 20021001 8

<h4>Objective</h4>To describe the use of large-scale gene expression profiles to distinguish broad categories of myopathy and subtypes of inflammatory myopathies (IM) and to provide insight into the pathogenesis of inclusion body myositis (IBM), polymyositis, and dermatomyositis.<h4>Methods</h4>Using Affymetrix GeneChip microarrays, the authors measured the simultaneous expression of approximately 10,000 genes in muscle specimens from 45 patients in four major disease categories (dystrophy, cong ...[more]

PMID: 12391344

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Project description:Molecular profiles of muscle tissue in patients with inflammatory myopathies Keywords: other

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