Unknown,Transcriptomics,Genomics,Proteomics

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ApoD modulation mouse cerebellar transcriptome


ABSTRACT: The lipocalin Apolipoprotein D (ApoD), known to protect the nervous system against oxidative stress (OS) in model organisms, is up-regulated early in the mouse brain in response to the ROS generator paraquat (PQ). However, the processes triggered by this up-regulation have not been explored. We present here a study of the effect of ApoD on the early transcriptional changes upon OS in the mouse cerebellum using microarray profiling. ApoD-KO and transgenic mice over-expressing ApoD in neurons are compared to wild-type controls.

ORGANISM(S): Mus musculus

SUBMITTER: Gabriel Gutierrez 

PROVIDER: E-GEOD-28643 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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