Unknown,Transcriptomics,Genomics,Proteomics

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High-throughput sequencing of small RNAs from chicken embryos


ABSTRACT: We applied Illumina sequencing to identify microRNAs (miRNAs) and piwi-interacting small RNAs (piRNAs) in the pre- and post-gastrula chicken embryos, and simultaneously obtain a comprehensive expression profile of miRNAs at diverse developmental stages. Discovery and characterization of small RNA species from pre-gastrula and post-gastrula chicken embryos through deep sequencing

ORGANISM(S): Gallus gallus

SUBMITTER: Peng Shao 

PROVIDER: E-GEOD-28668 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Drastic expression change of transposon-derived piRNA-like RNAs and microRNAs in early stages of chicken embryos implies a role in gastrulation.

Shao Peng P   Liao Jian-You JY   Guan Dao-Gang DG   Yang Jian-Hua JH   Zheng Ling-Ling LL   Jing Qing Q   Zhou Hui H   Qu Liang-Hu LH  

RNA biology 20120201 2


Recent studies have shown that endogenous small RNAs regulate a variety of biological processes during vertebrate development; however, little is known about the role of small RNAs in regulating developmental signaling pathways during early embryogenesis. In this study, we applied Illumina sequencing to characterize an unexpected endogenous small RNA catalog and demonstrated a dramatic transition from transposon-derived piRNA-like small RNAs (pilRNAs) to microRNAs (miRNAs) in pre- and post-gastr  ...[more]

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