Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

Expression profiles of microRNAs in gastric cancer

ABSTRACT: We analyzed expression profiles of microRNAs from 22 paired gastric cancer and normal tissues and identified differentially expressed microRNAs. RNA from paired normal and tumor specimens in 22 gastric cancer patients were extracted and treated for microRNA microarray analysis.

ORGANISM(S): Homo sapiens

SUBMITTER: Chien-Wei Tseng

PROVIDER: E-GEOD-28700 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Integrative network analysis reveals active microRNAs and their functions in gastric cancer.

Tseng Chien-Wei CW Lin Chen-Ching CC Chen Chiung-Nien CN Huang Hsuan-Cheng HC Juan Hsueh-Fen HF

BMC systems biology 20110626

<h4>Background</h4>MicroRNAs (miRNAs) are a class of endogenous, small and highly conserved noncoding RNAs that control gene expression either by degradation of target mRNAs or by inhibition of protein translation. They play important roles in cancer progression. A single miRNA can provoke a chain reaction and further affect protein interaction network (PIN). Therefore, we developed a novel integrative approach to identify the functional roles and the regulated PIN of oncomirs.<h4>Results</h4>We ...[more]

PMID: 21703006

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Dataset Information

Expression profiles of microRNAs in gastric cancer

Publications

Integrative network analysis reveals active microRNAs and their functions in gastric cancer.

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