Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

Pancreatic cancer vs. paired normal control

ABSTRACT: The miRNA expression between normal and cancerous pancreatic tissues and identified preferentially expressed miRNAs. Two-condition experiment, pancreatic cancer vs. paired normal control. Biological replicates: 3 paired patients tissues.

ORGANISM(S): Homo sapiens

SUBMITTER: Wenzhang Wang

PROVIDER: E-GEOD-28862 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Downregulation of miR-132 by promoter methylation contributes to pancreatic cancer development.

Zhang Shuyu S Hao Jun J Xie Fang F Hu Xiangui X Liu Cong C Tong Jian J Zhou Jundong J Wu Jinchang J Shao Chenghao C

Carcinogenesis 20110610 8

MicroRNAs (miRNAs), which regulate gene expression by partial complementarity to the 3' untranslated region of their target genes, have been implicated in cancer initiation and progression. However, the molecular mechanism underlying the regulation of miRNA expression during pancreatic tumorigenesis has not been extensively reported. In this study, we first compared the miRNA expression in human pancreatic cancers and adjacent normal tissues by miRNA array and identified 12 differentially expres ...[more]

PMID: 21665894

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Dataset Information

Pancreatic cancer vs. paired normal control

Publications

Downregulation of miR-132 by promoter methylation contributes to pancreatic cancer development.

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