Unknown,Transcriptomics,Genomics,Proteomics

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Molecular profiling of primary lung carcinomas


ABSTRACT: This SuperSeries is composed of the following subset Series: GSE29016: Relation between smoking history and gene expression profiles in lung adenocarcinomas GSE29065: Landscape of somatic allelic imbalances and copy number alterations in human lung carcinoma Refer to individual Series

ORGANISM(S): Homo sapiens

SUBMITTER: Åke Borg 

PROVIDER: E-GEOD-29066 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Landscape of somatic allelic imbalances and copy number alterations in human lung carcinoma.

Staaf Johan J   Isaksson Sofi S   Karlsson Anna A   Jönsson Mats M   Johansson Leif L   Jönsson Per P   Botling Johan J   Micke Patrick P   Baldetorp Bo B   Planck Maria M  

International journal of cancer 20121020 9


Lung cancer is the worldwide leading cause of death from cancer and has been shown to be a heterogeneous disease at the genomic level. To delineate the genomic landscape of copy number alterations, amplifications, loss-of-heterozygosity (LOH), tumor ploidy and copy-neutral allelic imbalance in lung cancer, microarray-based genomic profiles from 2,141 tumors and cell lines including adenocarcinomas (AC, n = 1,206), squamous cell carcinomas (SqCC, n = 467), large cell carcinomas (n = 37) and small  ...[more]

Publication: 1/2

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