Unknown,Transcriptomics,Genomics,Proteomics

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Exon-Level Expression Data from Primary Human B Cells and Lymphoblastoid Cell Lines (LCLs) on HuEx and U133 2.0 plus Platforms


ABSTRACT: Eptstein-Barr Virus, an oncogenic herpesvirus, infects and immortalizes human B cells in culture into indefinitely-prolerifating LCLs. We examined the gene expression of primary B cells during the process of infection and growth transformation at the exon level to analyze virus-induced changes in expression and exon usage. 4 samples each of total RNA were extracted from purified resting B Cells and monoclonal LCLs, for a total of 8. These samples were subjected to either Human Exon Array 1.0 or Affymetrix U133 2.0 plus. Data was then RMA normalized and analyzed using SplicerEx

ORGANISM(S): Homo sapiens

SUBMITTER: Luftig Laboratory 

PROVIDER: E-GEOD-29301 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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