Ontology highlight
ABSTRACT:
ORGANISM(S): Saccharomyces cerevisiae
SUBMITTER: Audrey Gasch
PROVIDER: E-GEOD-2969 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Lyons T J TJ Gasch A P AP Gaither L A LA Botstein D D Brown P O PO Eide D J DJ
Proceedings of the National Academy of Sciences of the United States of America 20000701 14
The Zap1p transcription factor senses cellular zinc status and increases expression of its target genes in response to zinc deficiency. Previously known Zap1p-regulated genes encode the Zrt1p, Zrt2p, and Zrt3p zinc transporter genes and Zap1p itself. To allow the characterization of additional genes in yeast important for zinc homeostasis, a systematic study of gene expression on the genome-wide scale was used to identify other Zap1p target genes. Using a combination of DNA microarrays and a com ...[more]