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Gene expression comparison among spleen dendritic cells, brain microglia, brain dendritic cells and bone marrow monocytes

ABSTRACT: To understand the functional relationship between brain dendritic cells (brain DCs) and other myeloid cells, we compared the gene expression profile of m/chDCs to that of bone marrow monocytes, brain microglia and classical spleen CD8+ and CD8- DCs. In order to obtain enough brain DCs for mRNA extraction, we expanded brain DCs with in vivo Flt3L treatment before purification. This study includes data from FACs Aria-purified brain DCs, bone marrow monocytes, brain microglia and classical spleen CD8+ and CD8- DCs. The genearray was performed to compare expression of cell surface endocytic receptor, cytokine receptors, TLRs, transcription factors, molecules for antigen processing and presentation. Each Series consists of 3 individuall samples

ORGANISM(S): Mus musculus

SUBMITTER: Kang Liu

PROVIDER: E-GEOD-29949 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Gene expression comparison among spleen dendritic cells, brain microglia, brain dendritic cells and bone marrow monocytes

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