Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Marcin Piechota
PROVIDER: E-GEOD-30305 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Piechota M M Korostynski M M Sikora M M Golda S S Dzbek J J Przewlocki R R
Genes, brain, and behavior 20120411 4
The molecular alterations that underlie the long-lasting behavioural effects of drugs of abuse, such as psychomotor sensitization and physical dependence, are still not known. Moreover, it is not known which molecular effects are similar for addictive drugs from various pharmacological classes. In this study, we utilized whole-genome microarray profiling to evaluate the detailed time-course of transcriptional alterations in the mouse striatum during chronic treatment with heroin (HER) and metham ...[more]