Unknown,Transcriptomics,Genomics,Proteomics

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Transcriptional profiling of the Neurospora crassa Δcre-1 mutant (FGSC 10372) compared to the wild type strain (FGSC 2489) in response to minimal medium or Avicel medium


ABSTRACT: In filamentous ascomycete fungi, the utilization of alternate carbon sources is influenced by the zinc finger transcription factor CreA/CRE-1, which encodes a carbon catabolite repressor protein homologous to Mig1 from Saccharomyces cerevisiae. In Neurospora crassa, deletion of cre-1 results in increased secretion of amylase and β-galactosidase. Here, we determined the CRE-1 regulon by investigating the transcriptome of a Δcre-1 strain compared to wild type when grown on Avicel versus minimal medium (MM). Our data provide comprehensive information on the CRE-1 regulon in N. crassa and contribute to deciphering the global role of carbon catabolite repression in filamentous ascomycete fungi during plant cell wall deconstruction. Two-condition experiment (minimal medium vs. Avicel medium) of the Δcre-1 mutant strain compared to the wild type strain. Cy3 and Cy5 dye swaps were performed.

ORGANISM(S): Neurospora crassa

SUBMITTER: Jianping Sun 

PROVIDER: E-GEOD-30313 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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