Ontology highlight
ABSTRACT:
ORGANISM(S): Escherichia coli
SUBMITTER: Thomas Wood
PROVIDER: E-GEOD-30692 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Hu Ying Y Benedik Michael J MJ Wood Thomas K TK
Environmental microbiology 20111026 3
Antitoxins are becoming recognized as proteins that regulate more than their own synthesis; for example, we found previously that antitoxin MqsA of the Escherichia coli toxin/antitoxin (TA) pair MqsR/MqsA directly represses the gene encoding the stationary-phase sigma factor RpoS. Here, we investigated the physiological role of antitoxin DinJ of the YafQ/DinJ TA pair and found DinJ also affects the general stress response by decreasing RpoS levels. Corroborating the reduced RpoS levels upon prod ...[more]