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Role and function of MYC in BCR-ABL1 driven pre-B cells

ABSTRACT: In order to investigate the function of MYC in ALL, we isolated bone marrow cells from conditional MYC knockout mice and transformed them with BCR-ABL1. In a second transduction the BCR-ABL1 driven pre-B cells were transformed either with CRE or empty vector control. Three days post transduction, total RNA of GFP positive sorted cells were extracted and subjected to gene expression analysis.

ORGANISM(S): Mus musculus

SUBMITTER: Markus Müschen

PROVIDER: E-GEOD-30928 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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