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Unknown,Transcriptomics,Genomics,Proteomics

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Multiple roles for CodY in the type strain Bacillus cereus ATCC 14579

ABSTRACT: Comparison of the B cereus codY deletion mutant with wild type strain (ATCC 14579) One condition design comparision of mutant vs wild type including a dye swap, 4 biological replicate

ORGANISM(S): Bacillus cereus ATCC 14579

SUBMITTER: Akos Kovacs

PROVIDER: E-GEOD-31017 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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CodY, a pleiotropic regulator, influences multicellular behaviour and efficient production of virulence factors in Bacillus cereus.

Lindbäck Toril T Mols Maarten M Basset Coraline C Granum Per Einar PE Kuipers Oscar P OP Kovács Ákos T ÁT

Environmental microbiology 20120428 8

In response to nutrient limitation in the environment, the global transcriptional regulator CodY modulates various pathways in low G+C Gram-positive bacteria. In Bacillus subtilis CodY triggers adaptation to starvation by secretion of proteases coupled to the expression of amino acid transporters. Furthermore, it is involved in modulating survival strategies like sporulation, motility, biofilm formation, and CodY is also known to affect virulence factor production in pathogenic bacteria. In this ...[more]

PMID: 22540344

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