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Essential role of gastric gland mucin in preventing gastric cancer in mice

ABSTRACT: To elucidate the molecular mechanism by which A4gnt-null mice develop gastric adenocarcinoma, gastric mucosa was isolated from the stomachs of wild-type and A4gnt-null mice, and microarray analysis was performed. Total RNA was isolated from the gastric mucosa stripped from the muscular layer of the glandular stomach of A4gnt-null and wild-type mice at 5, 10, and 50 weeks of age (one mouse per each group was analyzed).

ORGANISM(S): Mus musculus

SUBMITTER: Jun Nakayama

PROVIDER: E-GEOD-31074 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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