Unknown,Transcriptomics,Genomics,Proteomics

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Role of ECAT15-2/Dppa2 in lung development


ABSTRACT: This SuperSeries is composed of the following subset Series: GSE31581: ECAT15-2/Dppa2 deficient ESCs GSE31582: ECAT15-2/Dppa2 transgenic rescue into ECAT15-2/Dppa2 deficient ESCs GSE31583: Lung of ECAT15-2/Dppa2 deficient embryo at E18.5 Refer to individual Series

ORGANISM(S): Mus musculus

SUBMITTER: Shinya Yamanaka 

PROVIDER: E-GEOD-31584 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Essential roles of ECAT15-2/Dppa2 in functional lung development.

Nakamura Tomonori T   Nakagawa Masato M   Ichisaka Tomoko T   Shiota Arufumi A   Yamanaka Shinya S  

Molecular and cellular biology 20110906 21


Many transcription factors and DNA binding proteins play essential roles in the development of organs in which they are highly and/or specifically expressed. Embryonic stem cell (ESC)-associated transcript 15-1 (ECAT15-1) and ECAT15-2, also known as developmental pluripotency-associated 4 (Dppa4) and Dppa2, respectively, are enriched in mouse ESCs and preimplantation embryos, and their genes encode homologous proteins with a common DNA binding domain known as the SAP motif. Previously, ECAT15-1  ...[more]

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