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Expression data from EMRSA-15 treated with and without manuka honey

ABSTRACT: Manuka honey has been shown to inhibit growth in EMRSA-15 by inhibiting cell division, the mode of actin is currently unclear. We used microarrays to detail the difference in global gene expresson following treatment of cells with honey. We identified distinct classes of up and down regulated genes EMRSA-15 were harvested 4 hours after exposure to treatment for RNA extraction and hybridization on Affymetrix microarrays. Control and honey treated cells were investigates, three biological replicates were used for each sample.

ORGANISM(S): Staphylococcus aureus

SUBMITTER: Peter Giles

PROVIDER: E-GEOD-31592 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Synergy between oxacillin and manuka honey sensitizes methicillin-resistant Staphylococcus aureus to oxacillin.

Jenkins Rowena E RE Cooper Rose R

The Journal of antimicrobial chemotherapy 20120301 6

<h4>Objectives</h4>Honey is an ancient wound remedy that has recently been introduced into modern clinical practice in developed countries. Manuka honey inhibits growth of methicillin-resistant Staphylococcus aureus (MRSA) by preventing cell division. In Gram-negative bacteria a synergistic interaction between honey and antibiotics has been suggested. We aimed to determine the effect of manuka honey on oxacillin resistance in MRSA.<h4>Methods</h4>Inhibition of MRSA by manuka honey and oxacillin ...[more]

PMID: 22382468

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