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Expression data from B6, Sle1b and Sle1b.BACSlamf6-H1 CD4+ T cells

ABSTRACT: We recently showed that the Slamf6 protein isoform Slamf6-H1 markedly diminishes T cell–dependent disease upon introduction of a Slamf6-H1–expressing transgene into the lupus-prone Sle1b mouse, which lacks this isoform. In this study we purified CD4+ T cells from Sle1b, Sle1b.Slamf6-H1, or B6 mice and a global gene expression profile was analyzed. Comparison of isolated cells from three strains of mice (12wk old females) at three time points of anti-CD3 activation with three biological replicates for each group (unless indicated otherwise).

ORGANISM(S): Mus musculus

SUBMITTER: Marton Keszei

PROVIDER: E-GEOD-31733 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Expression data from B6, Sle1b and Sle1b.BACSlamf6-H1 CD4+ T cells

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