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Global transcriptomics of enterotoxigenic E. coli strain E24377A

ABSTRACT: ETEC is an important human pathogen. Although the mechanism of diarrhea is known in ETEC, the regulatory networks are less understood. This study was conducted to understand the global expression of ETEC isolate E24377A under different growth and environmental conditions. ETEC E24377A was grown in LB or LB+bile salts (3% w/v). For each condition, three biological replicates were combined into a single sample.

ORGANISM(S): Escherichia coli E24377A

SUBMITTER: Jason Sahl

PROVIDER: E-GEOD-31805 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Analysis of global transcriptional profiles of enterotoxigenic Escherichia coli isolate E24377A.

Sahl Jason W JW Rasko David A DA

Infection and immunity 20120103 3

Enterotoxigenic Escherichia coli (ETEC) is an important pathogenic variant (pathovar) of E. coli in developing countries from a human health perspective, causing significant morbidity and mortality. Previous studies have examined specific regulatory networks in ETEC, although little is known about the global effects of inter- and intrakingdom signaling on the expression of virulence and colonization factors in ETEC. In this study, an E. coli/Shigella pan-genome microarray, combined with quantita ...[more]

PMID: 22215741

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E. coli strain E24377A

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