Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of mouse model of human asthma exposed to ragweed pollen


ABSTRACT: This project investigates the mechanisms that underlie asthma-related phenotypes associated with allergen exposure. See http://www.hopkins-genomics.org/asthma/asthma006/index.html; The goal of the experiment was to identify genes that change their levels of expression as a consequence of challenge with allergen. The experiments utilized a murine model of human asthma that employed BALB/CJ mice. In this particular sensitization-challenge protocol, the response produced by BALB/CJ mice is representative of a majority of the mouse strains tested. The antigen complex used to sensitize and challenge the mice was ragweed pollen an allergen that is highly relevant to human disease. Experiment Overall Design: 40 samples: 2 time points, 2 strains, allergen and PBS control

ORGANISM(S): Mus musculus

SUBMITTER: Eric Hoffman 

PROVIDER: E-GEOD-3184 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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