Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Akira Hirasawa
PROVIDER: E-GEOD-32095 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Ichimura Atsuhiko A Hirasawa Akira A Poulain-Godefroy Odile O Bonnefond Amélie A Hara Takafumi T Yengo Loïc L Kimura Ikuo I Leloire Audrey A Liu Ning N Iida Keiko K Choquet Hélène H Besnard Philippe P Lecoeur Cécile C Vivequin Sidonie S Ayukawa Kumiko K Takeuchi Masato M Ozawa Kentaro K Tauber Maithé M Maffeis Claudio C Morandi Anita A Buzzetti Raffaella R Elliott Paul P Pouta Anneli A Jarvelin Marjo-Riitta MR Körner Antje A Kiess Wieland W Pigeyre Marie M Caiazzo Roberto R Van Hul Wim W Van Gaal Luc L Horber Fritz F Balkau Beverley B Lévy-Marchal Claire C Rouskas Konstantinos K Kouvatsi Anastasia A Hebebrand Johannes J Hinney Anke A Scherag Andre A Pattou François F Meyre David D Koshimizu Taka-aki TA Wolowczuk Isabelle I Tsujimoto Gozoh G Froguel Philippe P
Nature 20120219 7389
Free fatty acids provide an important energy source as nutrients, and act as signalling molecules in various cellular processes. Several G-protein-coupled receptors have been identified as free-fatty-acid receptors important in physiology as well as in several diseases. GPR120 (also known as O3FAR1) functions as a receptor for unsaturated long-chain free fatty acids and has a critical role in various physiological homeostasis mechanisms such as adipogenesis, regulation of appetite and food prefe ...[more]