Transcriptional landscape of Candida parapsilosis
Ontology highlight
ABSTRACT:
ORGANISM(S): Candida parapsilosis
SUBMITTER: Geraldine Butler
PROVIDER: E-GEOD-32714 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Using RNA-seq to determine the transcriptional landscape and the hypoxic response of the pathogenic yeast Candida parapsilosis.
Guida Alessandro A Lindstädt Claudia C Maguire Sarah L SL Ding Chen C Higgins Desmond G DG Corton Nicola J NJ Berriman Matthew M Butler Geraldine G
BMC genomics 20111222
<h4>Background</h4>Candida parapsilosis is one of the most common causes of Candida infection worldwide. However, the genome sequence annotation was made without experimental validation and little is known about the transcriptional landscape. The transcriptional response of C. parapsilosis to hypoxic (low oxygen) conditions, such as those encountered in the host, is also relatively unexplored.<h4>Results</h4>We used next generation sequencing (RNA-seq) to determine the transcriptional profile of ...[more]
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