Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Johanna Barclay
PROVIDER: E-GEOD-33381 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Barclay Johanna L JL Husse Jana J Bode Brid B Naujokat Nadine N Meyer-Kovac Judit J Schmid Sebastian M SM Lehnert Hendrik H Oster Henrik H
PloS one 20120521 5
Shiftwork is associated with adverse metabolic pathophysiology, and the rising incidence of shiftwork in modern societies is thought to contribute to the worldwide increase in obesity and metabolic syndrome. The underlying mechanisms are largely unknown, but may involve direct physiological effects of nocturnal light exposure, or indirect consequences of perturbed endogenous circadian clocks. This study employs a two-week paradigm in mice to model the early molecular and physiological effects of ...[more]