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Transcription profiling of human umbilical vein endothelial cells treated with fullerene

ABSTRACT: Control untreated versus fullerene-treated HUVECs Experiment Overall Design: Total RNA was isolated from HUVECs treated with or without C60(OH)24 (100 micro g/ml, 24 h). Two independent experiments were performed.

ORGANISM(S): Homo sapiens

SUBMITTER: Naoharu Iwai

PROVIDER: E-GEOD-3364 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Cytotoxicity of water-soluble fullerene in vascular endothelial cells.

Yamawaki Hideyuki H Iwai Naoharu N

American journal of physiology. Cell physiology 20060111 6

Nanoscale materials are presently under development for diagnostic (nanomedicine) and electronic purposes. In contrast to the potential benefits of nanotechnology, the effects of nanomaterials on human health are poorly understood. Nanomaterials are known to translocate into the circulation and could thus directly affect vascular endothelial cells (ECs), causing vascular injury that might be responsible for the development of atherosclerosis. To explore the direct effects of nanomaterials on end ...[more]

PMID: 16407415

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