Browse
Submit Data
Databases
API
Help

Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcription profiling of rats (SHR) on normal and high salt plus +fat diets, at 2 vs. 8 weeks

ABSTRACT: Supporting microarray data for manuscript entitled "OSTEOPONTIN AND PAI-1 EXPRESSION IN MALIGNANT HYPERTENSION: SUPPRESSION BY p38 MAPK INHIBITORS" submitted to the HYPERTENSION journal. Experiment Overall Design: Male spontaneously hypertensive stroke-prone rats (SHR-SP) were obtained from Charles River (Raleigh, NC). At 11 weeks of age, the SHR-SP were randomized into 2 groups, and fed either powdered chow diet (Purina 5001) with water ad lib; or a high-salt/high-fat diet consisting of 1% NaCl in the drinking water and 24.5% fat in the chow (from Harlan TekLad, Madison, Wisconsin). 6 replicate animals per diet per time point.

ORGANISM(S): Rattus norvegicus

SUBMITTER: Shawn O'Brien

PROVIDER: E-GEOD-3403 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

ACCESS DATA

Json Xml

Similar Datasets

Proteomics of liver from mice fed high fat diet (HFD) or regular chow diet

Project description:Proteomics of liver tissue from mice fed a high fat diet (HFD) or regular chow diet. Data accompany our paper entitled “Dynamic Regulation of N6,2′-O-dimethyladenosine (m6Am) in Obesity” scheduled for publication in Nature Communications, 2021

2021-10-27 | PXD029280 | Pride

Transcription profiling of liver of SHR/Izm (spontaneously hypertensive rat) fed high fat high colesterol diet for 4 weeks between 12 and 16 weeks of age

Project description:gene expression profiling of liver of SHR/Izm (spontaneously hypertensive rat) fed high fat high colesterol diet for 4 weeks or normal chow

2014-04-03 | E-MTAB-2468 | biostudies-arrayexpress

Transcription profiling of retroperitoneal adipose of SHR/Izm (spontaneously hypertensive rat) fed high fat high colesterol diet for 4 weeks between 12 and 16 weeks of age

Project description:gene expression profiling of retroperitoneal adipose of SHR/Izm (spontaneously hypertensive rat) fed high fat high colesterol diet for 4 weeks or normal chow

2014-04-03 | E-MTAB-2467 | biostudies-arrayexpress

Transcription profiling of liver and white adipose tissue from mice fed standard or test diets with or without monosodium glutamate in their water

Project description:C57BL/6J mice were from The Jackson Laboratory (Maine, USA) and were housed/caged and fed a standard chow diet until 6 weeks of age whereupon they were placed in one of 4 different dietary regimens for a period of 3 weeks prior to mating. Mice were housed under pathogen-free conditions of 21± 1°C, 40 to 60% humidity, and a 12 h-12 h light/dark cycle. The 4 diet regimens used in this study were: [1] ad lib Standard Chow (Control diet) with ad lib drinking water. [2] Ad lib Standard Chow, with ad lib drinking water containing 0.64 mg/ml (97 mg/Kg body weight) monosodium glutamate (MSG diet). [3] Ad lib Test Diet Purina 5001 with 20% 55-HFCS (5B4K, Purina, USA), and ad lib drinking water (HFCS diet). [4] Ad lib Purina 5001 with 20% 55-HFCS, and ad lib drinking water containing 0.64 mg/ml (97 mg/K body weight) monosodium glutamate (HFCS+MSG diet). See Table 1 for diet composition. Following mating, the 4 groups of dams were maintained on their respective diets throughout the gestation and nursing period. Male offspring used in these experiments were weighed, then weaned onto the same diets and maintained in this regimen until they reached either 16 or 32 weeks of age. Total RNA was prepared from the liver and visceral white adipose tissue (WAT) taken from 16-week-old mice in the 4 different diet groups using Qiagen RNeasy Kit (Qiagen USA) according to the manufacturers instructions and stored at -80 o C.<br>

2009-10-01 | E-MEXP-1909 | biostudies-arrayexpress

Effect of six different diets on liver gene expression

Project description:Male and female mice (Bl6/J) were fed a chow diet (control 1 and control 2) or a High fat diet (HFD) or a Choline deficient High fat diet (CD HFD) or a Western Diet (WD) or a Western Diet supplemented with glucose and fructose in drinking water (WD glucose fructose) for 15 weeks.

2022-10-31 | GSE159090 | GEO

SHR-SP rats on Normal and High Salt+Fat diets, 2 vs. 8 weeks

Project description:Supporting microarray data for manuscript entitled "OSTEOPONTIN AND PAI-1 EXPRESSION IN MALIGNANT HYPERTENSION: SUPPRESSION BY p38 MAPK INHIBITORS" submitted to the HYPERTENSION journal. Keywords: timecourse, diet

2005-10-04 | GSE3403 | GEO

A Proteomic Study of Salmonella Infection and High Fat Diet on Mouse Liver using Data-Independent Acquisition Mass Spectrometry

Project description:Data-independent acquisition of mouse liver with four treatments: normal chow diet and healthy (1-5), normal chow diet and inoculated with Salmonella (6-11), high fat diet and healthy (12-16), and high fat diet and inoculated with Salmonella (17-21).

2023-05-07 | MSV000091877 | MassIVE

Effect of Fumonisin B1 exposure on hepatic gene expression in mice fed a regular diet (CHOW) and in mice fed a High Fat Diet (HFD).

Project description:This experiment was designed to investigate the effect of Fumonisin B1 exposure on liver gene expression in male mice fed a regular diet (Chow group) and in obese mice which were fed a High fat diet (HFD). The Fumonisin B1 was provided through the drinking water.

2023-09-01 | GSE208735 | GEO

microRNA expression profiles in myocardium of diet-induced obesity rat

Project description:Diet induced obesity in rat was associated with myocardial dysfunction, hypertension and fibrosis. This study aimed to explore microRNA expression profiles in diet obesity-induced rat myocardium. Wistar rats were feed normal chow or high-fat diet for 20 weeks. After that, cardiac function was evaluated by echocardiography. Left ventricular myocardium was harvest to assess the extent of hypertension and fibrosis, meanwile, the left ventricular microRNA expression was analyzed using Agilent Rat miRNA microarray. Significant cardiac dysfunction, hypertension and fibrosis were found in diet-induced obesity rats as compared with normal diet rats. rno-miR-141-3p and rno-miR-144-3p were also significantly increased in myocardium of diet-induced obesity rat. These findings suggest that specific miRNA differences may contribute to the alteration in cardiac function, hypertension and fibrosis which responses to diet-induced obesity.

2020-01-07 | GSE143168 | GEO

Comparison of the effects upon gene expression of i.v. injection of plasma exosomes isolated from mice fed with differemt diets

Project description:We isolated plasma exosomes from mice fed for 6 weeks with either standard chow, a high-fat diet or standard chow with sucrose supplemented drinking water. We injected these exosomes into control mice fed standard chow and sacrificed them 72 h after the injection for tissue analysis We used microarrays to detail the global changes of gene expression induced by the injected exosomes in liver, adipose and muscle tissues

2022-12-31 | GSE202854 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data