Ontology highlight
ABSTRACT:
ORGANISM(S): Rattus norvegicus
SUBMITTER: Yoji Sato
PROVIDER: E-GEOD-3420 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Yokoyama Utako U Sato Yoji Y Akaike Toru T Ishida Seiichi S Sawada Junichi J Nagao Taku T Quan Hong H Jin Meihua M Iwamoto Mari M Yokota Shumpei S Ishikawa Yoshihiro Y Minamisawa Susumu S
Physiological genomics 20070717 1
Retinoic acid (RA), a metabolite of vitamin A, has been proposed to regulate vascular remodeling and reactivity of the ductus arteriosus (DA). Using rat Affymetrix GeneChips, we found that a considerable number of genes in DA varied their expression levels in accordance with developmental mode: namely, preterm-, term-, and postnatal-dominant clusters. Among a total of 8,740 probe sets, maternal vitamin A administration (MVA) changed the expression levels of 91 genes (116 probe sets) >2.5-fold. A ...[more]