MiRNA expression profile in murine
Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Andreas Schober
PROVIDER: E-GEOD-34648 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
The microRNA-342-5p fosters inflammatory macrophage activation through an Akt1- and microRNA-155-dependent pathway during atherosclerosis.
Wei Yuanyuan Y Nazari-Jahantigh Maliheh M Chan Lily L Zhu Mengyu M Heyll Kathrin K Corbalán-Campos Judit J Hartmann Petra P Thiemann Anna A Weber Christian C Schober Andreas A
Circulation 20130319 15
<h4>Background</h4>Atherosclerosis is a chronic inflammatory vascular disease driven by the subendothelial accumulation of macrophages. The mechanism regulating the inflammatory response in macrophages during atherogenesis remains unclear. Because microRNAs (miRNAs) play a crucial role in cellular signaling by posttranscriptional regulation of gene expression, we studied the miRNA expression profiles during the progression of atherosclerosis.<h4>Methods and results</h4>Using an miRNA real-time p ...[more]
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