Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Comparison of gene expression between wild type and AP2-L KO parasites


ABSTRACT: In the rodent malaria parasite Plasmodium berghei, we found that an AP2 family transcription factor designated AP2-L plays a critical role in the development of the liver stage. Using DNA microarray analysis we showed that the expression of several genes, including those of parasitophorous vacuole membrane proteins, was significantly decreased in the early liver stage of AP2-L-depleted parasites. Gene expression of P. berghei liver stages was compared between wild type and AP2-L KO parasites. Liver stage parasites were cultured for 24h using HepG2 cells. Ten and seven biologically independent experiments were performed for wild type and AP2-L KO parasites, respectively.

ORGANISM(S): Plasmodium berghei

SUBMITTER: masao yuda 

PROVIDER: E-GEOD-34877 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Similar Datasets

2012-04-30 | E-GEOD-34806 | biostudies-arrayexpress
2012-05-01 | GSE34877 | GEO
2012-05-01 | GSE34806 | GEO
2012-04-30 | E-GEOD-34878 | biostudies-arrayexpress
2022-08-05 | GSE198065 | GEO
2016-09-01 | GSE72399 | GEO
2015-10-01 | GSE66189 | GEO
2015-10-01 | GSE66188 | GEO
2010-06-20 | E-GEOD-18910 | biostudies-arrayexpress
2022-08-05 | GSE198070 | GEO