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Control of RelB during dendritic cell activation integrates canonical and non-canonical NFkB pathways

ABSTRACT: Dendritic cells (DC) play central roles in coordinating appropriate immune responses to pathogens. In the present study, the genes regulated by NFkB activators, RelB and cRel, in PAMP-induced bone marrow dendritic cells (BMDCs) activation was examined. Total RNA extracted from WT, relb-/-, crel-/-relb-/- bone marrow derived dendritic cells (BMDCs) were subjected to stimulation with CpG or Pam3CSK4.

ORGANISM(S): Mus musculus

SUBMITTER: Vincent Shih

PROVIDER: E-GEOD-34990 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Control of RelB during dendritic cell activation integrates canonical and non-canonical NFkB pathways

Project description:Dendritic cells (DC) play central roles in coordinating appropriate immune responses to pathogens. In the present study, the genes regulated by NFkB activators, RelB and cRel, in PAMP-induced bone marrow dendritic cells (BMDCs) activation was examined.

2012-10-01 | GSE34990 | GEO

Transcription factor NFAT1 regulates systemic autoimmunity through modulation of dendritic cell property

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Effect of Leishmania infantum infection on the gene expression of murine bone marrow-derived dendritic cells

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Transcriptional Remodeling Patterns in Murine Dendritic Cells Infected with Paracoccidioides brasiliensis: More Is Not Necessarily Better

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Comparison of RelB-/- and RelB+/- thymi

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2012-12-27 | E-GEOD-43154 | biostudies-arrayexpress

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