Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling by array of mouse lung from C57BL/6J and A/J mice during embryonic development


ABSTRACT: In this study, time dependent genome wide lung mRNA profiling changes were assessed using C57BL/6J and A/J mice. Through comprehensive bioinformatics and functional genomics analyses, we identified both temporal and strain dependent gene expression patterns, systemically mapped key regulators, bioprocesses, and transcriptional networks controlling lung maturation, providing the basis for new therapeutic strategies to enhance lung function in preterm infants. In this study, we designed a genome-wide mRNA expression time-course study from E15.5 to Postnatal Day 0 (PND0) using lung RNAs from C57BL/6J and A/J mice that differ significantly in gestational length.

ORGANISM(S): Mus musculus

SUBMITTER: Yan Xu 

PROVIDER: E-GEOD-35485 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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