Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Morgane RAVON
PROVIDER: E-GEOD-35673 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Babiarz Joshua E JE Ravon Morgane M Sridhar Sriram S Ravindran Palanikumar P Swanson Brad B Bitter Hans H Weiser Thomas T Chiao Eric E Certa Ulrich U Kolaja Kyle L KL
Stem cells and development 20120104 11
To gain insight into the molecular regulation of human heart development, a detailed comparison of the mRNA and miRNA transcriptomes across differentiating human-induced pluripotent stem cell (hiPSC)-derived cardiomyocytes and biopsies from fetal, adult, and hypertensive human hearts was performed. Gene ontology analysis of the mRNA expression levels of the hiPSCs differentiating into cardiomyocytes revealed 3 distinct groups of genes: pluripotent specific, transitional cardiac specification, an ...[more]