Design and use of multiplexed chemostat arrays
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ABSTRACT: We developed and validated a small-footprint array of miniature chemostats built from readily available parts for low cost. Physiological and experimental evolution results were similar to larger volume chemostats. The ministat array provides a compact, inexpensive, and accessible platform for traditional chemostat experiments, functional genomics, and chemical screening applications. Three experiments are gene expression comparisons between three ministat cultures and a single Sixfors sample. The four CGH arrays are individual clones evolved in four sulfate limitation ministats compared to a wt ancestor strain.
ORGANISM(S): Saccharomyces cerevisiae
SUBMITTER: Maitreya Dunham
PROVIDER: E-GEOD-36691 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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