Unknown,Transcriptomics,Genomics,Proteomics

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Expression profiling of Drosophila testes


ABSTRACT: We performed mRNA-seq of dissected testes of multiple Drosophila species and RNAi animals mRNA seq of testis

ORGANISM(S): Drosophila yakuba

SUBMITTER: Sidi Chen 

PROVIDER: E-GEOD-36764 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Reshaping of global gene expression networks and sex-biased gene expression by integration of a young gene.

Chen Sidi S   Ni Xiaochun X   Krinsky Benjamin H BH   Zhang Yong E YE   Vibranovski Maria D MD   White Kevin P KP   Long Manyuan M  

The EMBO journal 20120427 12


New genes originate frequently across diverse taxa. Given that genetic networks are typically comprised of robust, co-evolved interactions, the emergence of new genes raises an intriguing question: how do new genes interact with pre-existing genes? Here, we show that a recently originated gene rapidly evolved new gene networks and impacted sex-biased gene expression in Drosophila. This 4-6 million-year-old factor, named Zeus for its role in male fecundity, originated through retroposition of a h  ...[more]

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