Ontology highlight
ABSTRACT:
ORGANISM(S): Thermus thermophilus HB8
SUBMITTER: Akeo Shinkai
PROVIDER: E-GEOD-36881 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Agari Yoshihiro Y Sakamoto Keiko K Kuramitsu Seiki S Shinkai Akeo A
Journal of bacteriology 20120629 17
PfmR is one of four TetR family transcriptional regulators found in the extremely thermophilic bacterium, Thermus thermophilus HB8. We identified three promoters with strong negative regulation by PfmR, both in vivo and in vitro. PfmR binds pseudopalindromic sequences, with the consensus sequence of 5'-TACCGACCGNTNGGTN-3' surrounding the promoters. According to the amino acid sequence and three-dimensional structure analyses of the PfmR-regulated gene products, they are predicted to be involved ...[more]