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Rat brain microvessel SAGE

ABSTRACT: SAGE analysis of genes expressed in rat brain microvessels. Keywords: Novel gene identification Microvessels were pooled from 50 rats, a single SAGE library was constructed from the microvessel RNA

ORGANISM(S): Rattus norvegicus

SUBMITTER: Les Drewes

PROVIDER: E-GEOD-3696 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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The rat blood-brain barrier transcriptome.

Enerson Bradley E BE Drewes Lester R LR

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20051123 7

The blood-brain barrier (BBB) is the cellular interface between the circulating blood and neural environment, and is created by apposed endothelial cells and their intercellular tight junctions. Many aspects of how the BBB functions at the molecular level remain unresolved; therefore, we report for the first time a comprehensive gene expression profile of rat brain microvessels using serial analysis of gene expression (SAGE). We assembled a full and quantitative SAGE catalog containing 101,364 t ...[more]

PMID: 16306934

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