Butyrophilin 3A1 binds phosphorylated antigens and stimulates human TCR M-NM-3M-NM-4 cells.
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ABSTRACT: We used genetic approaches to identify butyrophilin 3A1 (BTN3A1) as the molecule that binds and presents phosphorylated antigens to VM-NM-39VM-NM-42 TCRM-bM-^@M-^Sexpressing cells. BTN3A1 represents a novel antigenM-bM-^@M-^Spresenting molecule for the activation of VM-NM-39VM-NM-42 TCRM-bM-^@M-^Sexpressing cells which play important roles in human tumor immunity and host defense. 3 replicates of 4 cell lines (12 samples total) were analysed. Data was RMA normalized, and genes that expressed above the negative control in all 4 cell lines from chromosome 6 considered for further analysis
ORGANISM(S): Homo sapiens
SUBMITTER: jinmiao chen
PROVIDER: E-GEOD-37634 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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