Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Viviane Praz
PROVIDER: E-GEOD-38303 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
James Faresse Nicole N Canella Donatella D Praz Viviane V Michaud Joëlle J Romascano David D Hernandez Nouria N
PLoS genetics 20121115 11
SNAP(c) is one of a few basal transcription factors used by both RNA polymerase (pol) II and pol III. To define the set of active SNAP(c)-dependent promoters in human cells, we have localized genome-wide four SNAP(c) subunits, GTF2B (TFIIB), BRF2, pol II, and pol III. Among some seventy loci occupied by SNAP(c) and other factors, including pol II snRNA genes, pol III genes with type 3 promoters, and a few un-annotated loci, most are primarily occupied by either pol II and GTF2B, or pol III and B ...[more]