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Expression data from E12.5 NSP cells, CTL v REST shRNA

ABSTRACT: REST is a master regulator of genes that are involved in the acqusition of neuronal fate. The role of REST is not well understood so we attempted to investigate the role of REST in the development of neural cells by analysing the genes that are upregulated when REST is knocked down via shRNA We used microarrays to assess the genes which were up and down regulated after REST is knocked down E12.5 NSP cells were infected with either control or REST shRNA expressing lentiviruses and collected after 6 days for RNA extraction

ORGANISM(S): Mus musculus

SUBMITTER: Matthew Covey

PROVIDER: E-GEOD-38538 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Expression data from E12.5 NSP cells, CTL v REST shRNA

Project description:REST is a master regulator of genes that are involved in the acqusition of neuronal fate. The role of REST is not well understood so we attempted to investigate the role of REST in the development of neural cells by analysing the genes that are upregulated when REST is knocked down via shRNA We used microarrays to assess the genes which were up and down regulated after REST is knocked down

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