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Gene expression in human germinal center light zone and dark zone B cells

ABSTRACT: Microarrays of gene expression in human germinal center light zone and dark zone B cells sorted according to the expression of cell surface molecules CD83 and CXCR4 We used microarray data to identify genes differentially expressed by B cells in the light and dark zones of germinal centers from human tonsil specimens. Germinal center B cells (CD19+CD38+IgD-) were sorted from pediatric tonsil discard specimens into light zone (CXCR4hi/CD83lo) and dark zone (CXCR4lo/CD83hi) populations, from which RNA was extracted

ORGANISM(S): Homo sapiens

SUBMITTER: Gabriel Victora

PROVIDER: E-GEOD-38697 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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